Sales Director, HDV Business Unit – Remote Job at Mirum Pharmaceuticals | Find My Remote

MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

POSITION SUMMARY

The Sales Director, HDV Business Unit will lead a highly specialized field team of Regional Account Managers (RAMs) tasked with preparing the U.S. market for the anticipated launch of Brelovitug for Hepatitis Delta Virus (HDV), pending regulatory approval. This role is responsible for advancing disease awareness, supporting account readiness, and helping to establish the foundation for appropriate patient identification and management in a market with profound unmet need.

HDV represents the most severe form of viral hepatitis, requiring Hepatitis B co-infection for replication and spread. Despite an estimated U.S. prevalence of ~40,000 patients and ~15,000 who are diagnosed, insured, and under care, there are currently no approved therapies in the U.S., underscoring the urgency and importance of this role.

This leader must excel at operating in ambiguity—defining strategy, building structure, and driving execution in a market that is still being shaped in real time.

JOB FUNCTIONS/RESPONSIBILITIES

Strategic Leadership

Build and lead the HDV team of 6 Regional Account Managers across key U.S. geographies
Develop and execute a pre-launch market development strategy focused on HDV disease awareness and diagnosis expansion
Identify and prioritize high-value accounts within key HDV geographies
Translate evolving epidemiology, market insights, and competitive dynamics into actionable, compliant field strategies
Create clarity from ambiguity by setting direction, establishing priorities, and adapting strategy as new information emerges

Market Development & Disease Education

Drive awareness of HDV as a severe, underdiagnosed condition requiring urgent intervention
Expand understanding of the relationship between HDV and Hepatitis B (HBsAg dependency)
Partner with KOLs and key institutions to support HDV screening, diagnosis, and referral pathways
Support initiatives to improve patient identification within the estimated ~40,000 patients under care

Account Engagement & Activation

Ensure strategic engagement across key stakeholders and health systems
Establish account plans focused on screening protocols, care pathways, and disease management readiness
Collaborate cross-functionally with Medical Affairs, Market Access, and Marketing to ensure aligned execution
Support accounts in enhancing (or operationalizing) HDV identification and management in the absence of established standards

Team Leadership & Development

Recruit, develop, and coach a high-impact team of RAMs
Set clear expectations aligned with pre-launch, non-promotional objectives
Foster a culture of accountability, agility, and mission-driven execution
Coach the team to operate effectively without fixed playbooks—encouraging problem-solving, adaptability, and proactive compliant decision-making
Lead through influence in a complex, cross-functional environment

Cross-Functional Collaboration

Serve as the field leadership voice in launch planning
Partner closely with:
- Medical Affairs on scientific exchange and KOL engagement (as appropriate and compliant)
- Market Access on payer readiness and coverage considerations
- Commercial leadership on launch readiness and execution
Align stakeholders around evolving strategies, even when data, timelines, or market conditions are still emerging

QUALIFICATIONS

Education/Experience:

Bachelor’s degree required; MBA or advanced degree preferred
7+ years of pharmaceutical/biotech experience, including field leadership
Proven success leading account-based or specialty field teams through ambiguity
Experience in rare disease, hepatology, infectious disease, or specialty launches
Demonstrated ability to build strategy in pre-launch environments
Strong understanding of U.S. healthcare systems, IDNs, and academic centers
Experience with Hepatitis B, liver disease, or transplant networks preferred
Launch experience in a market with low awareness/high unmet need
Strong KOL engagement and scientific fluence
Thrives in a fast-paced, dynamic, and collaborative environment
Able to travel frequently, up to 70% overnight travel and has a valid drivers’ license

KEY COMPETENCIES

Strategic thinker with strong execution discipline
Comfort leading through ambiguity—able to make decisions with incomplete information and adjust rapidly
Ability to build structure and momentum from the ground up
Exceptional leadership and team development skills
High emotional intelligence and stakeholder influence
Mission-driven mindset aligned to addressing critical unmet need
Ability to understand and effectively communicate scientific information within role and scope
Foster a culture of innovation, accountability, and entrepreneurial thinking

#LI-REMOTE

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.

Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.